何有文

2017-06-21


美国杜克大学医学中心免疫系终身正教授,美国免疫学家学会会员,教育部长江学者讲座教授,第四军医大学讲座教授,国家分子医学转化科学中心细胞重编程与免疫治疗中心主任,首席科学家。1986年第四军医大学医学学士,1989年军事医学科学院微生物与流行病学研究所免疫学硕士,1996年美国迈阿密大学医学院免疫学博士,1996-2000年在华盛顿大学免疫学系/霍华德休斯医学研究所做博士后研究。 2000年至今在杜克大学医学中心任职助理教授,终身教授,到正教授。现任Journal of Biological ChemistryImmunology, Cellular and Molecular Immunology,和Scientific Reports 编委,担任 Autophagy   Frontiers in Cell and Developmental Biology 的副主编。现任美国卫生部国家疫苗赔偿项目特聘专家,美国国立卫生研究院基金评审专家,中国科技部自然科学基金委评审专家以及30多种世界著名学术杂志如Nature, Nature Immunology等的评审人。何有文博士从事免疫学方面的研究30年,共在国际一流科学杂志发表文章110多篇。最近5年致力于肿瘤的临床免疫治疗,率先在广东暨南大学附属三九脑科医院开展世界首个高度个体化和精准化的脑肿瘤免疫治疗的临床研究,现在领导三个免疫治疗癌症的临床实验。 

You-Wen He, M.D. Ph.D., Professor of Immunology

Dr. You-Wen He received his M.D. from the Fourth Military Medical University in 1986 in China and his Ph.D. in Immunology from the University of Miami School of Medicine in 1996. He completed his postdoctoral training in Dr. Michael J. Bevan’s laboratory at HHMI/University of Washington and took an Assistant Professor position in the Department of Immunology at Duke University Medical Center in year 2000. Dr. He is currently a Professor of Immunology at Duke University Medical Center. His lab has been studying T cell biology in health and diseases. The current effort in his lab is focused on developing new strategies to treat cancers using immunotherapies. His lab is examining how antibodies/antagonists to complement receptors and the cytokine IL-10 are used to treat different tumors in animal models and human. Dr. He is also leading three highly personalized cancer immunotherapy clinical trials treating patients with glioblastoma multiforme and advanced solid tumors. He also studies the functional role of the fundamental intracellular process termed autophagy in T lymphocyte function.

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