陈宏武

2017-06-23


现任加州大学戴维斯终身教授,曾兼任加州大学戴维斯癌症中心分子肿瘤项目主任。陈教授擅长从事表观遗传因子和核受体为靶标的癌症治疗和转化医学研究,已经发现和鉴定多个具有治疗和诊断价值的靶标,是位卓有成就的癌症研究专家。最近发现了可用于治疗多种癌症的全新靶标-核受体RORγ,并开发了多个以RORγ为靶标的先导化合物。陈教授研究成果发表在权威期刊如Cell, Science,和Nature Medicine等,也获得了多个专利保护。

 Dr. Hongwu Chen is a professor at the University of California, Davis, School of Medicine and was a Molecular Oncology Program Director at the UC Davis Cancer Center. He runs a highly productive cancer research program with focus on identification of key epigenetic factors and nuclear receptors as effective therapeutic targets and potential biomarkers and publishes at the high-impact journals. One of his recent discoveries is the tumor-driving role of an orphan nuclear receptor RORgamma in multiple types of cancer. His team also developed several orally effective small-molecule inhibitors that are of therapeutic value for treatment of multiple types of therapeutics-resistant cancer.

 

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